Helicobacter Pylori Infection in Cases of Hyperemesisgravidarum; Updates

Background: One of the serious problem affecting pregnant females is Hyperemesis gravidarum. Different theories were suggested. But the main etiology is still unknown Objectives: To determine the incidence of Helicobacter pylori infection in cases of hyperemesis gravidarum. Patients and methods: case control study of 80 cases (40 case of HEG) and (40 case of normal pregnant females. Determination of Helicobacter pylori antibodies were done in serum and stool for the two studied groups. Results: 75% of cases of HEG were positive of Helicobacter pylori in stool samples and 37.50% of normal pregnant females. These results were statistically significant (p=0.001). The prevalence of HpIgG AB and HpSAB was 77.5% in the patients group with HEG, and 55.0% in control studied group (P=0.05). There was a significant difference between HEG cases and normal pregnancy as regards serum sodium (0.042). Conclusions: Infection by helicobacter pylori may be one of the risk factors for HEG. Helicobacter pylori AB in both serum and stool is higher in HEG cases than in normal pregnant females.